Psoriasis is non infectious, inflammatory disease of the skin. It is characterised by well defined erythematous plaques with adherent silvery scales.  
1-3 % of the population has this disease. More common in Europe and North America.Often seen between 15 to 40 yrs.  
Aetiology  Real aetiology is unknown. Genetic: If one parent is affected the offspring has 25% chance to develop the disease. If both parents are affected the chances rise to 60%.The disease has been found to have a genetic basis. On HLA phenotyping of the Chandigarh patients, a positive association was seen with HLA-B17 . However, familial occurrence was detected in only 2%.  
Common Patterns of Psoriasis:  

Plaque pattern: It is the most common type. The individual lesions are well demarcated and are red with dry silvery white scaling. Most common sites involved are scalp, elbow, knee and lower back.

Guttate Psoriasis
: Usually seen in the children and adolescents. The individual lesions of the rash are small and scaly. The bouts of guttate psoriasis clear in months but the patient may develop plaque pattern later.

Geographical tongue seen in 3.8% and Blepharitis in 5%.  
Scalp: This site is often involved. Areas of scaling are inter-spread with normal scalp. Significant hair loss occurs only if there is gross involvement.
Nails: Involvment of nails is common. Thimble pitting, Onycholysis (separation of nail from nail bed), Subungal hyperkeratosis are main changes seen in the nails. Involvement of nails reflect the extent of the disease elsewhere.
Flexures: Involvement of flexures like axillary folds and submammary folds are not scaly but red, glistening and symmetrical.
Palms: Psoriasis in the palms is poorly demarcated and is poorly erythematous.
Less common types of psoriasis are Napkin psoriasis and Localised pustular psoriasis in the palms and soles consisting of numerous small sterile pustules on erythematous base.  
Complications: Psoriatic Arthropathy is seen in 5 %. There may be distal small joint involvement mainly terminal interphalangeal joints of hands and toes. Single large joint arthropathy may also be seen which mimmics rheumatoid arthritis. Sacroiliac joint and lumbar spine involvement may also be seen.  
Serum copper levels are found to be higher while serum zinc levels were lower in Psoriatics as compared to controls.Urinary tract cell counts were significantly higher in Psoriatics.  
 Psoriasis ~ Treatment

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About Manbir & Gurpreet

Gurpreet Kaur’s journey in this world .... Gurpreet Kaur was a Musician. She was a singer and a composer of music. Her interest was composing and singing Gurbani Shabads in Indian Classical style. She sang Shabads in All the Raags mentioned in Sri Guru Granth Sahib Ji. She also taught Gurmat Sangeet at Gurmat Gian Missionary College, Jawadi, Ludhiana. Elder child to Pushpinder Kaur and Dr. Brig. Harminder Singh, was born in Amritsar on 13th Jan 1962. She attended various convent schools as a child because her father would get frequent Army postings as a dental surgeon. She graduated with Music Honors from Govt. College for Women, Chandigarh. Music was her hobby and she composed and sang Raag based Gurbani Shabads. Doing Kirtan was part of growing up nurtured by her parents. She learned music from her father Dr. Brigadier Harminder Singh who was a dental surgeon in Indian Army and a very good singer himself. Gurpreet’s Bhua (father’s sister), Ajit Kaur retied as a Head of Department of Music from Govt. College for Women Ludhiana, and was a renounced Punjabi singer of her time. Gurpreet Kaur also learned nuances of Indian Classical Music from Pandita Sharma. She was a mother of three children, and a grandmother. Her daughter Keerat Kaur is a Computer Engineer. Her two sons Gurkeerat Singh and Jaskeerat Singh are doctors in USA. Her daughter Keerat Kaur too was part of her group ~ Gurmat Gian Group. Gurpreet Kaur left this world at the age of 54yrs on 12th Sept 2016 in Baltimore USA. She had recorded around 25 cds of Gurbani Keertan. 'Raag Ratan' Album (6 CDs) is a Compilation of Shabads in All the 31 Sudh Raags of Sri Guru Granth Sahib Ji. 'Gauri Sagar' Album (3 CDs) is a Compilation of All forms of Raag Gauri in Sri Guru Granth Sahib Ji. 'Nanak Ki Malhaar' ~ ((3 CDs) is an album of Raag Malhar Shabads in various forms of Malhar. 'Gur Parsaad Basant Bana' ~ (3 CDs) is an album of Shabads in Raag Basant sung in various forms of Raag Basant. Har Ki Vadeyai Sarni Aayea Sewa Priya Kee Preet Piyaree Mohan Ghar Aavho Karo Jodariya Mo Kao Taar Le Raama Taar Le Tere Kavan Kavan Gun Keh Keh Gawan Mera Baid Guru Govinda Saajanrraa Mera Saajanrraa

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