Adverse effects of Amphetamines
Amphetamines are central nervous system stimulant. Amphetamines (dexedrine) are being miss used by many. Psychological dependence and tolerance may occur with amphetamines following prolonged use or high doses.
Amphetamines are used in the treatment of Attention-deficit hyperactivity disorder.
Amphetamines are indicated as an integral part of a total treatment program that includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with attention-deficit hyperactivity disorder, characterized by moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Due to their high potential for abuse, amphetamines are not recommended for use as appetite suppressants. Amphetamines should not be used to combat fatigue or to replace rest in normal subjects.
More frequent adverse effects
CNS stimulation – false sense of well-being; irritability; nervousness; restlessness; trouble in sleeping, drowsiness, fatigue, trembling, or mental depression may follow the stimulant effects.
With prolonged use or high doses
Cardiomyopathy – chest discomfort or pain; difficulty in breathing; dizziness or feeling faint; irregular or pounding heartbeat; unusual tiredness or weakness. Irregular heart beat.
Increase in blood pressure
Psychotic reactions – mood or mental changes
Less frequent adverse effects
Allergic reaction – skin rash or hives
Chest pain, fast or pounding heartbeat; increased sweating
Tourette’s syndrome – uncontrolled movements of the head, neck, arms, and legs
Hyperthermia – extremely high body temperature
Changes in sexual desire or decreased sexual ability
Constipation, diarrhea loss of appetite nausea stomach cramps or pain, weight loss, vomiting, dizziness lightheadedness headache; dryness of mouth or unpleasant taste.
Symptoms indicating possible withdrawal – after medication is discontinued
Mental depression; nausea stomach cramps or pain vomiting; trembling; unusual tiredness or weakness