|The following conditions predispose to loss of bone and increased susceptibility to osteoporosis and consequent fractures.
- Women with early menopause (40-45 years)
- Younger women with ovarian hormone failure Or bilateral oophorectomy ( removal of Ovaries ) before normal menopause.
- Women not receiving hormonal therapy for at least 5 years after menopause.
- Patients after prolonged corticoid treatment of more than 3 months.
- Primary hyperparathyroidism.
- Strong family history of osteoporosis.
- Men with hypogonadism.
- Patients who have received chemotherapy, especially for breast cancers and haematological cancers.
- Certain drugs enhance bone loss and render the patient susceptible to development of osteoporosis (e.g. corticoids, anti-convulsants, excessive doses of thyroid hormone, prolonged heparin therapy and anti-cancer drugs including high doses of methotrexate.
- Low Calcium in diet.
- Insufficient exposure to sunlight or not enough Vitamin D in diet.
- White or Eurasian ancestry.
- Caffeine (consistently more than three cups a day of coffee, tea, cola).
- Alcohol (consistently more than two drinks a day).
- Sedentary life style or prolonged bed rest.