Chronic Granulomatous Disease

Chronic Granulomatous Disease

Chronic Granulomatous Disease is a rare disease. It is estimated to occur once in 250,000 individuals. Most often CGD is inherited as an X-linked recessive pattern, although in about 40 percent of patients the disease is inherited with an autosomal recessive pattern.

Patients with CGD characteristically have increased infection. When patients with CGD become infected, they often have extensive inflammatory reactions despite the administration of appropriate antibiotics. Aphthous ulcers and chronic inflammation of the nares are usually present. Granulomas are frequent and can obstruct the gastrointestinal or genitourinary tracts. 

Blood in the placenta contains bone marrow stem cells. This fact was made use by the doctors to treat a rare disease known as Chronic Granulomatous Disease in a child. Dr. Andrew Cant, director of the children’s bone marrow transplant unit claim it is the first time the treatment has been used.July 04, 2002A 3-year-old north Wales boy, Tom Stretch with a life-threatening condition has been cured after a pioneering treatment involving his mother’s placenta. This child was suffering from CGD and needed a bone marrow transplant to combat a blood defect which had left him unable to fight off germs. The boy had a series of serious pneumonias and an inflamed bowel. 

He needed bone marrow transplant and there was no immediately suitable bone marrow donor. After his mother Joanne gave birth to his sister Hannah at Ysbyty Glan Clwyd in north Wales in November last year doctors preserved the placenta. The blood was kept in a bank at Newcastle General Hospital’s specialist children’s bone marrow transplant unit. Doctors decided to try an infusion of the placenta blood containing the stem cells as an alternative to bone marrow transplant.

The treatment to infuse the cord blood into the vein took place 16 weeks ago and experts claim that Tom’s condition has now been cured and he is free of infection and his bowel inflammation is settling rapidly.

Its first time anywhere in the world that this technique has been used to treat CGD.

Stem Cell

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About Manbir & Gurpreet

Gurpreet Kaur’s journey in this world .... Gurpreet Kaur was a Musician. She was a singer and a composer of music. Her interest was composing and singing Gurbani Shabads in Indian Classical style. She sang Shabads in All the Raags mentioned in Sri Guru Granth Sahib Ji. She also taught Gurmat Sangeet at Gurmat Gian Missionary College, Jawadi, Ludhiana. Elder child to Pushpinder Kaur and Dr. Brig. Harminder Singh, was born in Amritsar on 13th Jan 1962. She attended various convent schools as a child because her father would get frequent Army postings as a dental surgeon. She graduated with Music Honors from Govt. College for Women, Chandigarh. Music was her hobby and she composed and sang Raag based Gurbani Shabads. Doing Kirtan was part of growing up nurtured by her parents. She learned music from her father Dr. Brigadier Harminder Singh who was a dental surgeon in Indian Army and a very good singer himself. Gurpreet’s Bhua (father’s sister), Ajit Kaur retied as a Head of Department of Music from Govt. College for Women Ludhiana, and was a renounced Punjabi singer of her time. Gurpreet Kaur also learned nuances of Indian Classical Music from Pandita Sharma. She was a mother of three children, and a grandmother. Her daughter Keerat Kaur is a Computer Engineer. Her two sons Gurkeerat Singh and Jaskeerat Singh are doctors in USA. Her daughter Keerat Kaur too was part of her group ~ Gurmat Gian Group. Gurpreet Kaur left this world at the age of 54yrs on 12th Sept 2016 in Baltimore USA. She had recorded around 25 cds of Gurbani Keertan. 'Raag Ratan' Album (6 CDs) is a Compilation of Shabads in All the 31 Sudh Raags of Sri Guru Granth Sahib Ji. 'Gauri Sagar' Album (3 CDs) is a Compilation of All forms of Raag Gauri in Sri Guru Granth Sahib Ji. 'Nanak Ki Malhaar' ~ ((3 CDs) is an album of Raag Malhar Shabads in various forms of Malhar. 'Gur Parsaad Basant Bana' ~ (3 CDs) is an album of Shabads in Raag Basant sung in various forms of Raag Basant. Har Ki Vadeyai Sarni Aayea Sewa Priya Kee Preet Piyaree Mohan Ghar Aavho Karo Jodariya Mo Kao Taar Le Raama Taar Le Tere Kavan Kavan Gun Keh Keh Gawan Mera Baid Guru Govinda Saajanrraa Mera Saajanrraa

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